Here's a link to the Gems of Knowledge page that discusses this in detail. It does keep changing throughout the game, but some things remain constant. This is discussed on the forum at times as well.Can anyone give me an idea as to what the maximum numbers of squares you will need for different buildings
Example: General consensus for factories is 40 squares per Tier as a good average. So, if your boosts are marble, crystal, and gems you want 40 squares devoted to each of those factory types. If your marble are 2x2, you'll need 10, but once they are 5x4 you'll only need 2. For a variety of reasons that change as you go through the chapters (some chapters require more Tier 2 goods; others are heavy on the Tier 3 requirements; sometimes you win a bunch of event bldgs that give goods, etc) you'll need to tweak this every so often to meet your needs.
That site has loads of helpful information, so once you get over there, poke around a bit...